RESUMO
This study reports a case of a 56-year-old white male, retired coal-miner, diagnosed with chromoblastomycosis lasting 20 years. The infection site was the burnt skin of the back. For many years the patient had not undertaken any treatment believing that the lesion had been a burn scar. A gradual increase in lesion size prompted the patient to start therapy. The diagnosis was made by histopathological examination and mycological culture. Identification of the causative agent at the species level was achieved by sequence analysis of the internal transcribed spacer (ITS) region and D1/D2 domains of the 26S rDNA. To our knowledge, this is the first documented case of chromoblastomycosis caused by Fonsecaea monophora in temperate Europe, outside the endemic area for the disease. This finding is highly significant for understanding the routes of infection of chromoblastomycosis and radically revises the traditional view of the natural ecology of the etiological agents of the disease.
Assuntos
Cromoblastomicose/epidemiologia , Doenças Endêmicas , Antifúngicos/uso terapêutico , Ascomicetos/isolamento & purificação , Dorso/microbiologia , Dorso/patologia , Queimaduras/microbiologia , Cromoblastomicose/diagnóstico , Europa (Continente)/epidemiologia , Humanos , Itraconazol/uso terapêutico , Masculino , Pessoa de Meia-Idade , Pele/microbiologia , Pele/patologiaRESUMO
A case of rare form of colliquative tuberculosis in a 58-year old man is presented. The preliminary diagnosis was made on the basis of clinical observation. Confirmation was achieved after obtaining a significant improvement of the general and local condition as a positive results after antituberculous therapy.
Assuntos
Antituberculosos/uso terapêutico , Tuberculose Cutânea/diagnóstico , Tuberculose Cutânea/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
A rare case of porphyria cutanea tarda (PCT) in an 11-year-old boy is presented. The clinical manifestations were typical. Results of porphyrin analyses of urine and serum with a fluorescence emission maximum around 398 nm revealed a pattern consistent with PCT.